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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF4G2
All Species:
13.64
Human Site:
S432
Identified Species:
42.86
UniProt:
P78344
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78344
NP_001409.1
907
102362
S432
M
G
G
K
F
M
K
S
Q
G
L
S
Q
L
Y
Chimpanzee
Pan troglodytes
XP_001170632
1033
115739
S558
M
G
G
K
F
M
K
S
Q
G
L
S
Q
L
Y
Rhesus Macaque
Macaca mulatta
XP_001093873
1176
131101
S701
M
G
G
K
F
M
K
S
Q
G
L
S
Q
L
Y
Dog
Lupus familis
XP_851579
701
79569
L284
N
K
N
Q
V
P
K
L
Q
P
Q
I
T
M
I
Cat
Felis silvestris
Mouse
Mus musculus
Q62448
906
102087
S431
M
G
G
K
F
M
K
S
Q
G
L
S
Q
L
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515837
496
55369
A79
N
A
Q
K
W
I
P
A
R
S
T
R
R
D
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394628
920
105173
Q430
N
Y
Q
G
K
H
N
Q
Q
Q
H
N
S
P
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782944
923
103756
Q420
Q
R
Q
D
R
G
Q
Q
D
K
P
Y
G
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.8
76.9
77.1
N.A.
99.1
N.A.
N.A.
51
N.A.
N.A.
N.A.
N.A.
N.A.
37.9
N.A.
28.9
Protein Similarity:
100
87.8
77.1
77.2
N.A.
99.7
N.A.
N.A.
51.8
N.A.
N.A.
N.A.
N.A.
N.A.
56.7
N.A.
48
P-Site Identity:
100
100
100
13.3
N.A.
100
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
100
100
26.6
N.A.
100
N.A.
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
0
0
0
0
0
13
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
13
0
0
0
0
13
0
0
0
0
13
13
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
50
50
13
0
13
0
0
0
50
0
0
13
13
13
% G
% His:
0
0
0
0
0
13
0
0
0
0
13
0
0
0
0
% H
% Ile:
0
0
0
0
0
13
0
0
0
0
0
13
0
0
13
% I
% Lys:
0
13
0
63
13
0
63
0
0
13
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
13
0
0
50
0
0
50
0
% L
% Met:
50
0
0
0
0
50
0
0
0
0
0
0
0
13
0
% M
% Asn:
38
0
13
0
0
0
13
0
0
0
0
13
0
0
0
% N
% Pro:
0
0
0
0
0
13
13
0
0
13
13
0
0
13
0
% P
% Gln:
13
0
38
13
0
0
13
25
75
13
13
0
50
0
13
% Q
% Arg:
0
13
0
0
13
0
0
0
13
0
0
13
13
0
0
% R
% Ser:
0
0
0
0
0
0
0
50
0
13
0
50
13
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
13
0
13
0
0
% T
% Val:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
13
0
0
0
0
0
0
0
0
0
13
0
0
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _